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Subject A Research Team of KU Anam Hospital Visualizes Anti-Inflammatory Effect of Exercise
Selection News Date 2020-06-29 Read 56

For the First Time in the World, a Research

Team Led by Professor Sung-Eun Kim of

the Department of Nuclear Medicine of

Korea University Anam Hospital Visualizes

Anti-Inflammatory Effect of Exercise 

  

 

Measure Inflammatory Activity of Visceral Fat During 3 Months of

 

Exercise Training

 

 

Can Confirm Treatment Goals and Progress Through PET/CT

 

 

It is widely known that exercise has significant health benefits to the obese and

 

reduces the risk of cardiovascular disease. However, there was no clear evidence

 

as to whether the inflammatory activity of visceral fat, a key mechanism of the

 

harmful effects of obesity, was affected by exercise. 

 

 

Recently, the anti-inflammatory effect of exercise on the inflammatory activity

 

of visceral fat in obese women has been identified for the first time in the world,

 

garnering attention in academia. 

 

 

A research team led by Prof. Sung-Eun Kim of Department of Nuclear

 

Medicine of Korea University Anam Hospital (Prof. Hong-Seog Seo of

 

Cardiovascular Center of Korea University Guro Hospital, Prof. Sung-Eun Kim

 

and Prof. Kisoo Pahk of Department of Nuclear Medicine of Korea University

 

Anam Hospital) studied the inflammatory activity in visceral adipose tissue with

 

23 obese women who participated in a three-month regular exercise program. 

 

 

The three months exercise training program consisted of everyday aerobic

 

exercise and muscle‚Äźresistant training such as 30 minutes of brisk walking and

 

20 minutes of running. As a result, the team could clearly see that the

 

inflammatory activity in visceral adipose tissue was reduced to almost half. This

 

is the first time in the world to measure the change in inflammatory activity in

 

visceral fat caused by exercise with a nuclear medicine imaging modality. While

 

the visceral fat inflammatory activity decreased, the body mass index (BMI)

 

decreased from an average of 27.5 to 25.3, and the waist circumference

 

decreased from an average of 83.2cm to 81.3cm. 

 

 

“I expect the study to help understand the mechanism of exercise’s beneficial

 

effects on health,” Prof. Kim stated. 

 

 

“In the treatment of obesity, the reduction of the inflammatory activity of

 

visceral fat is recognized as an important treatment goal. 18F-FDG PET/CT, a

 

nuclear medicine imaging modality that can visualize inflammatory activity in

 

visceral adipose tissue, is expected to be very useful.” Prof. Pahk said. 

 

 

The study “Exercise training reduces inflammatory metabolic activity of

 

visceral fat assessed by 18F-FDG PET/CT in obese women” was published in

 

the latest issue of Clinical Endocrinology, an international journal, attracting

 

wide interests from international academia.

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